Comments on: Are DNA-polymer-conjugates finally taking off?

By: kayesdee

kayesdee — Tue, 24 Feb 2009 21:40:17 +0000

gekfluka, as you already know, published yields are somewhat untrustworthy, often enough. And especially in this field, 30% is quite nice, but sounds high.

Don't have the paper at hand, but my key point still is valid: this is by far not mainstream chemistry yet. If it ever will reach into the stages of chumping out real products.

By: gekfluka

gekfluka — Wed, 18 Feb 2009 16:39:58 +0000

I was very excited to discover this field of DNA block copolymers when I first read the paper from Alemdaroglu et al.

I would just like to add that I was unable to reproduce the synthesis with the same yield (they describe around 30% and I got only 1%), did they tell us everything about that?

By: (Almost) Polymer of the month (May 2007): DNA with a twist at the power of goo

(Almost) Polymer of the month (May 2007): DNA with a twist at the power of goo — Sat, 12 May 2007 12:25:07 +0000

[…] which reminded me of my DNA-richer days, long ago they seem. If you remember my last comment on DNA-Polymer conjugates you know that DNA can do all sorts of nice things for polymer chemists as well as material […]

By: andherrm

andherrm — Thu, 19 Apr 2007 16:45:46 +0000

if you are interested in these kind of DNA block copolymer materials please have a look at the following papers:

Alemdaroglu FE, Ding K, Berger R, Herrmann A: DNA-Templated Synthesis in Three Dimensions: Introducing a Micellar Scaffold for Organic Reactions: Angew. Chem. Int. Ed. 2006, 45: 4206-4210.
Ding K, Alemdaroglu FE, BÃ¶rsch M, Berger R, Herrmann A: Engineering the Structural Properties of DNA Block Copolymer Micelles by Molecular Recognition: Angew. Chem. Int. Ed. 2007, 46: 1172-1175.
Alemdaroglu FE, Safak M, Berger R, Herrmann A: DNA Block Copolymers: Chem. Commun. 2007, 1358-1359.
Safak M, Alemdaroglu FE, Li Y, Ergen E, Herrmann A: Polymerase Chain Reaction as a Novel Tool for the Preparation of Block Copolymers: Adv. Mat. 2007, in press.
Alemdaroglu FE, Herrmann A: DNA Meets Synthetic Polymers â€“ Highly Versatile Hybrid Materials: Org. Biomol. Chem. 2007, 5: 1311 - 1320. (Invited Review)

By: andrewsun

andrewsun — Tue, 27 Feb 2007 08:14:35 +0000

BTW how to change my password?

By: andrewsun

andrewsun — Tue, 27 Feb 2007 05:43:29 +0000

I also started to notice the fast moving front of DNA block copolymer after that post. I guess this is based on the development of DNA chemistry these years (rather than that of DNA biology earlier). And yes the first thing emerged in my mind after seeing Herrmann's paper was 'progammable materials', which encorporating DNA into polymer chemistry may provide.